Gene edited (GE) crop plants with DNA deletions are not GM

TAL effector protein wrapped up around a DNA double helix
Bacterial leaf blight of rice (source: IRRI)
Targeted deletions in the rice genome (Li et al. 2012)

Further readings

  • Boch J, Scholze H, Schornack S, Landgraf A, Hahn S, Kay S, Lahaye T, Nickstadt A, & Bonas U (2009). Breaking the code of DNA binding specificity of TAL-type III effectors. Science (New York, N.Y.), 326 (5959), 1509–12 PMID: 19933107
  • Bogdanove AJ, & Voytas DF (2011). TAL effectors: customizable proteins for DNA targeting. Science (New York, N.Y.), 333(6051), 1843–6 PMID: 21960622
  • Moscou MJ, & Bogdanove AJ (2009). A simple cipher governs DNA recognition by TAL effectors. Science (New York, N.Y.), 326 (5959) PMID: 19933106
  • Li T, Liu B, Spalding MH, Weeks DP, & Yang B (2012). High-efficiency TALEN-based gene editing produces disease-resistant rice. Nature biotechnology, 30 (5), 390–2 PMID: 22565958
  • Schornack, S & Boch, J (2010). Unraveling a 20-Year Enigma. MPMI Reporter.
  • Tesson L, Usal C, Ménoret S, Leung E, Niles BJ, Remy S, Santiago Y, Vincent AI, Meng X, Zhang L, Gregory PD, Anegon I, & Cost GJ (2011). Knockout rats generated by embryo microinjection of TALENs. Nature biotechnology, 29 (8), 695–6 PMID: 21822240

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KamounLab

KamounLab

Biologist; passionate about science, plant pathogens, genomics, and evolution; loves travel, food, and sports; nomad and hunter-gatherer.